Cipla does not disclose pricing of drug, Hetero to supply its version of Remdesivir at Rs. 5,000- Rs. 6,000 per vial
New Delhi: Drugmakers Cipla and Hetero yesterday said they had launched generic versions of Remdesivir to treat COVID-19 patients.
Both the companies received regulatory approval of Remdesivir from the Drug Controller General of India (DCGI), on June 20, for restricted emergency use as part of the accelerated approval process considering the urgent and unmet medical need.
Cipla launched its version of Remdesivir 100 mg vial (injectable) under brand name CIPREMI, while Hetero launched the product under the brand name COVIFOR. Cipla has not disclosed the pricing of the drug, Hetero said it would supply its version of Remdesivir at Rs. 5,000- Rs. 6,000 per vial.
Hetero has said it wants to ensure the five-day treatment or six vials should cost not more than Rs. 30,000 per patient. “As part of the risk management plan, Cipla will provide training on the use of the drug, informed patient consent documents, conduct post-marketing surveillance as well as conduct a Phase IV clinical trial on Indian patients,” Cipla said in a statement.
The company said it would be commercialising Remdesivir through its own facilities and partnered sites. “The drug will be supplied through Government and open market channels, to ensure equitable distribution,” the company added.
Sources say Cipla has partnered with BDR Pharma to manufacture the drug. Hetero said it had enough stocks to supply to the present needs of the country.
In May, Gilead Sciences entered into voluntary non-exclusive license with Cipla, Hetero, Jubilant Life Sciences, Mylan and Pakistani company to manufacture and market Remdesivir in 127 countries including India. Gilead later entered a similar agreement with Zydus Cadila and Dr. Reddy’s.
The Indian Health Ministry protocol says Gilead’s antiviral drug may be considered in patients with moderate disease or those on oxygen. The protocol advises giving the drug against people with liver disease, kidney failure, pregnant or lactating women, and children under 12 years. Remdesivir usage is for five days, 200 mg IV (intravenous) on day 1 followed by 100 mg IV daily for five days.